Lorenzo's Oil (1993)

Lorenzo Odone, a Virginia 5-year-old, develops a degenerative nerve disease so rare that nobody is working on a cure, so his parents decide to immerse themselves in research and tackle the problem themselves.

Director: George Miller

Cast: Nick Nolte, Susan Sarandon, Peter Ustinov, Kathleen Wilhoite, Gerry Bamman, Margo Martindale, James Rebhorn, Ann Hearn, Maduka Steady, Mary Wakio, Don Suddaby, Colin Ward, LaTanya Richardson Jackson, Jennifer Dundas, William Cameron, Becky Ann Baker, Mary Pat Gleason, David Shiner