Molly (1999)

A bachelor becomes the unwilling guardian of his autistic, intellectually disabled sister; then an experimental treatment works a dramatic change in her brain and his attitude.

Director: John Duigan

Cast: Elisabeth Shue, Aaron Eckhart, Jill Hennessy, Thomas Jane, D.W. Moffett, Elizabeth Mitchell, Robert Harper, Elaine Hendrix, Michael Paul Chan, Lucy Liu, Jon Pennell, Sarah Wynter, Lauren Richter, Tanner Lee Prairie, Nicholas Pryor, Mark Phelan, Jay Acovone, Julie Ariola