The Fountain (2006)

As a modern-day scientist, Tommy is struggling with mortality, desperately searching for the medical breakthrough that will save the life of his cancer-stricken wife, Izzi.

Director: Darren Aronofsky

Cast: Hugh Jackman, Rachel Weisz, Sean Patrick Thomas, Ellen Burstyn, Mark Margolis, Stephen McHattie, Fernando Hernandez, Cliff Curtis, Donna Murphy, Ethan Suplee, Richard McMillan, Lorne Brass, Abraham Aronofsky, Renee Asofsky, Anish Majumdar, Janique Kearns, Boyd Banks, Alex Bisping